Clinical Research Trials

Help move medicine forward and improve the lives of others.

MedSleep is a leader in conducting research and clinical trials with the goal of advancing the treatment options in sleep medicine.

Our clinical trials are conducted in compliance with International Conference on Harmonisation (ICH)-Good Clinical Practice (GCP), regulatory guidance and standard operating procedures.

Our highly skilled staff includes clinical research coordinators, a patient recruitment specialist and board registered polysomnographic technologists.

In addition, we have a full-time medical director/principal investigator and more than 20 consulting physicians with specialties in sleep medicine, psychiatry, psychology, neurology, respirology and internal medicine.


MedSleep clinical research has the following advantages:

  • Expertise in Phase 2 to 4 clinical trials including proof of concept clinical trial
  • Health Canada inspected facility – assessed as fully compliant
  • Database with over 12,000 patients
  • Multiple locations across Canada and headquartered in Toronto, Ontario, one of the world’s most diverse populations
  • Total of 48 state-of-the-art modern polysomnography beds (6 in Toronto, 6 in Thornhill, 6 in Etobicoke, 9 in Kingston, 6 in Niagara, 6 in Nanaimo, 3 in Calgary, 3 in Edmonton and 3 in Halifax)
  • Experience in conducting clinical trials in partnership with hospitals, clinical research organizations and for major pharmaceutical and biotechnology companies
  • Strategic partnerships with a central laboratory and pulmonary clinic
  • Experience in central and local research ethics board submissions

For more information, contact us at [email protected].


Do You Qualify?

You may qualify to participate in any of our clinical research studies if you meet the study criteria.

Narcolepsy with or without Cataplexy

Obstructive Sleep Apnea with CPAP Intolerance or Refusal

SynAIRgy Study-Comparing a Fixed Dose Combination of Aroxybutynin/Atomoxetine (AD109) to Placebo in Obstructive Sleep Apnea.


Obstructive Sleep Apnea (OSA) is a common and serious sleep disorder in which breathing is repeatedly interrupted during sleep. OSA occurs when the airway collapses as you breathe in. This can cause breathing to be paused from several seconds to over a minute. While many people use continuous positive airway pressure (CPAP) machines to manage their OSA, these systems can be cumbersome and awkward for some. Right now, doctors at select centers throughout the US and Canada are conducting a new research study that may be able to help. The study is for an investigational oral medication for OSA taken nightly at bedtime.


Why Participate?


If you’re living with obstructive sleep apnea (OSA) and have not had lasting success with CPAP machines or other treatments, you may qualify for a new clinical study. If you qualify and choose to join the study, you will receive:

  • Evaluations of your OSA condition from a local physician specialist
  • Study-related care and study medication at no cost (health insurance is not required)
  • Compensation for your time and travel to attend study visits
  • The opportunity to help advance OSA research and treatment options to potentially benefit others living with OSA


See If You Qualify


To see if you might qualify for the study, and to connect with a local study center to learn more, please take the questionnaire below.

  1. How did you first learn about the study?

    • Internet – Facebook/Instagram

    • Internet – Web Search/Browsing

    • Friend/Family

    • Doctor Recommendation

    • Postcard

    • Brochure/Poster

    • Church Bulletin

    • Bingo Bugle

    • Community Event

    • Festival

    • Local establishment (store, barbershop, etc.)

    • Other


  1. Please enter your zip code:

  1. Based on your zip code, the following study location(s) have been found in your area. Please select the location that is most convenient for you:

    • Toronto Study Site – City: Toronto

    • Ottawa Study Site – City: Ottawa

  1. Are you at least 18 years old?

    • Yes

    • No

  1. Have you been diagnosed by a doctor as having obstructive sleep apnea (OSA)?

    • Yes – and I have previously had a sleep study

    • Yes – but I have not previously had a sleep study

    • No – I have never been diagnosed by a doctor as having OSA

  1. Do you often feel fatigued or run down?

    • Yes

    • No

  1. How much are you bothered by fatigue?

    • Not at all

    • A little bit

    • Somewhat

    • Quite a bit

    • Very much

  1. Please use the Body Mass Index (BMI) calculator to find your current BMI:

    • < 18.5

    • 18.5 – 25.0

    • 25.1 – 32.0

    • 32.1 – 42.0

    • > 42.0

  1. Which of the following best describes your experience with your PAP machine use (such as CPAP or BiPAP)?

    • I use my PAP machine without any problems

    • I don’t use my PAP machine as often as I should

    • I can’t or do not want to use a PAP machine

    • I do not currently have a PAP machine

  1. Does your work involve shift-work that causes your regular sleep time to be during the day, or do you operate commercial vehicles?

    • Yes

    • No

  1. Do you typically smoke more than 10 cigarettes per day or 2 cigars per day?

    • Yes

    • No

  1. Are you currently pregnant or are you planning to become pregnant or father a child within the next year?

    • Yes

    • No

  1. Do you currently have an implanted device to treat your sleep apnea such as an Inspire device?

    • Yes

    • No

  1. Do you have any of the following medical conditions? (Please check all that apply). If none, please select ‘NONE of these’ at the bottom.

    • Narcolepsy

    • Daily oxygen therapy

    • Severe heart disease

    • Neurological disorder (Parkinson’s Disease, seizure disorder, neuromuscular disease)

    • NONE of these

Research Trial Application

Please complete the form below and click the Submit button if you would like to be put on a list to be contacted when the next trial begins.