Research Trials

MedSleep is a leader in conducting research and clinical trials with the goal of advancing the treatment options in sleep medicine.

Our clinical trials are conducted in compliance with International Conference on Harmonisation (ICH)-Good Clinical Practice (GCP), regulatory guidance and standard operating procedures.

Our highly skilled staff includes clinical research coordinators, a patient recruitment specialist and board registered polysomnographic technologists.

In addition, we have a full-time medical director/principal investigator and more than 20 consulting physicians with specialties in sleep medicine, psychiatry, psychology, neurology, respirology and internal medicine.

MedSleep clinical research has the following advantages:

  • Expertise in Phase 2 to 4 clinical trials including proof of concept clinical trial
  • Health Canada inspected facility – assessed as fully compliant
  • Database with over 12,000 patients
  • Multiple locations across Canada and headquartered in Toronto, Ontario, one of the world’s most diverse populations
  • Total of 48 state-of-the-art modern polysomnography beds (6 in Toronto, 6 in Thornhill, 6 in Etobicoke, 9 in Kingston, 6 in Niagara, 6 in Nanaimo, 3 in Calgary,  3 in Edmonton and 3 in Halifax)
  • Experience in conducting clinical trials in partnership with hospitals, clinical research organizations and for major pharmaceutical and biotechnology companies
  • Strategic partnerships with a central laboratory and pulmonary clinic
  • Experience in central and local research ethics board submissions

For more information, contact us at research@medsleep.com.

Do You Qualify?

You may qualify to participate in any of our clinical research studies if you meet the study criteria.

Stanford Centre for Sleep Sciences and Medicine

This study will be used to create a database on sleep related data, which will include genetic and phenotype data to gain a better understanding of the genetic architecture of sleep and to help improve the detection, treatment and prevention of sleep disorders.

To qualify for this study, participants must:

  • Be 13 years and older
  • Have a consult appointment scheduled at one of the MedSleep locations
  • Be willing to wear a heart rate, activity, and sleep tracker watch for 2 weeks
  • Give a blood sample
  • Complete some sleep questionnaires
  • Willing to undergo all study assessments

Qualified participants will receive:

  • Medical care
  • The wearable sleep device to keep after study participation ends

Narcolepsy with Cataplexy

We are currently seeking volunteers who may be interested in participating in a clinical trial involving an investigational medication (a medication that is being tested).

  • To show the effectiveness of the investigational medicine in treatment of cataplexy in subjects with narcolepsy
  • To show effectiveness of the investigational medicine in the treatment of excessive daytime sleepiness in subjects with narcolepsy

To qualify, you must:

  • Be 18-70 years old
  • Have a primary diagnosis of narcolepsy with cataplexy
  • Currently untreated or treated with or without anticataleptic
  • Not be diagnosed with narcolepsy which is secondary to another medical condition
  • Not be pregnant, nursing or lactating
  • Not have a history of substance use
  • Not have moderate or severe Obstructive Sleep Apnea
  • Not have any presence of unstable or clinically significant medical condition such as uncontrolled hypothyroidism, behavioural or psychiatric disorder
  • Not have participated in a clinical trial in the last 30 days
  • Being able to commit to research visits and assessments approximately 9 clinic visits over a period of 18- 20 weeks

Qualified participants will receive:

  • The investigational medication
  • Medical care
  • Compensation for your time and travel

Weight Loss

We are seeking volunteers for a clinical study involving a novel treatment that has been shown to cause weight loss in overweight and obese people.

To qualify, you must:

  • Must be ≥ 18 years
  • Be overweight or obese (BMI ≥ 30 kg/m² or ≥ 27 kg/m²)
  • Must have at least one of the following: blood pressure, dyslipidemia, obstructive sleep apnea or heart disease
  • Not have type 1 or type 2 diabetes
  • Not using or have taken any medication for the treatment of obesity in the past 90 days
  • Not be pregnant, nursing or lactating
  • Not have a history of substance use
  • Not participated in a clinical trial in past 90 days
  • Be able to attend 15 clinic visits over a period of 75 weeks (18months)

Qualified Participants will receive:

  • The investigational medication
  • Medical care
  • Diet and exercise counseling
  • Compensation for your time and travel will also be provided

Insomnia

We are currently seeking volunteers who may be interested in participating in a clinical trial involving an investigational medication (a medication that is being tested).

To qualify, you must:

  • You are male or female ≥ 18 years of age
  • Have problems falling and staying asleep for at least the past 3 months
  • Do not regularly nap throughout the day
  • Have no significant medical illness, mental illness or cognitive impairment
  • Not be pregnant, nursing or lactating
  • No history of substance use
  • Must not be a shift worker
  • Not participated in a clinical study in the past 3 months
  • Willing to comply with all aspects of the study visits and requirements with 12 clinic visits over a period of 3 months

If you qualify for any of these clinical studies, you may receive the following:

  • Complete sleep and/or medical evaluation (including routine blood tests and comprehensive physical examination)
  • Study medication and all study-related tests at no cost
  • Compensation may be provided for your time and/or travel

Call or email us so we can discuss further whether you would be eligible for any of the clinical trials.

Please note that if you do not qualify for a research study at this time, you can still enter your information to be included in our database to be contacted for any future research trials for which you may qualify.ac

Research Trial Application

Please complete the form below and click the Submit button if you would like to be put on a list to be contacted when the next trial begins.